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What is of celebrex?
of celebrex blocks the action of the COX-2 enzyme, which plays a key role in
pain and inflammation.
What is of celebrex used for?
of celebrex is used for relief of acute pain in adults, menstrual pain in
women, and for pain, inflammation, and stiffness of osteoarthritis and
rheumatoid arthritis in adults.
How does of celebrex work?
of celebrex blocks inflammation- and pain-producing COX-2.
When should I take of celebrex?
Take of celebrex as prescribed. If you're prescribed a daily dose of
of celebrex, take it every day. Maintaining a consistent level of
of celebrex in your body helps manage arthritis pain, inflammation, and
stiffness, or acute pain. of celebrex can be taken at any time of the day.
Are there any side effects when taking of celebrex?
The most common side effects include indigestion, diarrhea, and abdominal pain.
In rare cases, serious stomach problems, such as bleeding, can occur without
warning.
Are there any effects of taking of celebrex with other medications?
Some medications, when taken together, can interact to increase or decrease
their effects. Be sure to tell your doctor or pharmacist about all the
medications you take, including over-the-counter drugs, vitamins, supplements,
and herbal products. Taking of celebrex and aspirin together may increase
your risk for developing stomach ulcers compared with taking of celebrex
alone
Why is of celebrex prescribed?
of celebrex is prescribed for acute pain, menstrual cramps, and the pain and
inflammation of osteoarthritis and rheumatoid arthritis. It is a member of a
new class of nonsteroidal anti-inflammatory drugs (NSAIDs) called COX-2
inhibitors. Like older NSAIDs such as Motrin and Naprosyn, of celebrex is
believed to fight pain and inflammation by inhibiting the effect of a natural
enzyme called COX-2. Unlike the older medications, however, it does not
interfere with a similar substance, called COX-1, which exerts a protective
effect on the lining of the stomach. Therefore, of celebrex may be less
likely to cause the bleeding and ulcers that sometimes accompany sustained use
of the older NSAIDs.
of celebrex has also been found to reduce the number of colorectal polyps (growths
in the wall of the lower intestine and rectum) in people who suffer from the
condition called familial adenomatous polyposis (FAP), an inherited tendency
to develop large numbers of colorectal polyps that eventually become cancerous.
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Most important fact about of celebrex
Like other NSAID medication, of celebrex could increase the chance of having
a heart attack or stroke, possibly resulting in death. The risk is greater if
you have heart disease or use NSAIDs for a long time. It's important to
discuss the risks and benefits of using of celebrex with your doctor and to
use the lowest effective dose for the shortest amount of time possible.
Although of celebrex is easy on the stomach, it still poses some degree of
risk—especially if you've had a stomach ulcer or gastrointestinal bleeding in
the past. All NSAIDs, including of celebrex, can cause serious—and even
life-threatening—ulcers and bleeding in the stomach and intestines. These side
effects can happen without symptoms and may occur at any time during treatment.
If you've ever had ulcers or stomach bleeding, make sure the doctor is aware
of it. And be sure to alert the doctor if you develop any digestive problems
or notice a change in your bowel movement (such as blood in the stool or black,
sticky stools).
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How should you take of celebrex?
Take of celebrex exactly as prescribed. You can take it with or without food.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for your next dose, skip
the one you missed and go back to your regular schedule. Do not take 2 doses
at the same time.
--Storage instructions...
Store at room temperature.
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of celebrex side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine if it
is safe for you to continue taking of celebrex.
Side effects may include:
Abdominal pain, diarrhea, headache, indigestion, nausea, respiratory infection,
sinus inflammation
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Why should of celebrex not be prescribed?
Do not take of celebrex right before or after heart bypass surgery (also
called coronary artery bypass graft, or CABG).
In addition, you should not use of celebrex if you are allergic to
sulfonamide drugs such as sulfadiazine, sulfisoxazole, Gantanol, and
Thiosulfil. Also avoid the drug if you've ever suffered an asthma attack, face
and throat swelling, or skin eruptions after taking aspirin or other NSAIDs.
If you find that you are allergic to of celebrex, you will not be able to use
it.
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Special warnings about of celebrex
Remember to tell your doctor about any stomach ulcers or bleeding you've had
in the past. Also alert your doctor if you develop any digestive problems,
swelling, or rash. The chance of developing a stomach ulcer or bleeding while
taking of celebrex increases if you also take steroid drugs or blood thinners,
smoke, drink alcohol, or use of celebrex or other NSAID medications for a
long time. The risk is also greater if you're older or in poor health. Be sure
the doctor is aware of your full medical history.
If you have asthma, use of celebrex with caution. It could trigger an attack,
especially if you are also sensitive to aspirin.
If you are taking a steroid medication for your arthritis, do not discontinue
it abruptly when you begin therapy with of celebrex. of celebrex is not a
substitute for such drugs.
of celebrex has been known to cause kidney or liver problems, particularly in
people with an existing condition. If you have such a disorder, take
of celebrex with caution. If you develop symptoms of liver poisoning, stop
taking the drug and see your doctor immediately. Warning signs include nausea,
fatigue, itching, yellowish skin, pain in the right side of the stomach, and
flu-like symptoms.
If you are prone to anemia (loss of red blood cells), make sure the doctor
knows about it. of celebrex occasionally fosters this problem.
of celebrex sometimes causes water retention, which can aggravate swelling,
high blood pressure, and heart failure. Use of celebrex with caution if you
have any of these conditions.
There is no proof that of celebrex reduces the odds of cancer in people who
take the drug for FAP. Although of celebrex can reduce the number of growths,
you'll still need the other treatments and frequent checkups that this
condition requires.
The safety and effectiveness of of celebrex have not been tested in children
under 18.
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Possible food and drug interactions when taking of celebrex
If of celebrex is taken with certain other drugs, the effects of either could
be increased, decreased, or altered. It is especially important to check with
your doctor before combining of celebrex with the following:
ACE-inhibitors (a type of blood pressure and heart medication, including such
drugs as Capoten, Vasotec, and Prinivil)
Blood thinning agents such as Coumadin
Fluconazole (Diflucan)
Furosemide (Lasix)
Lithium (Eskalith, Lithobid)
Thiazide diuretics (water pills) such as hydrochlorothiazide and Dyazide
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